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  • 10 Feb 2022 2:30 PM | Anonymous member

    BIO Alabama is poised to be a key player in state’s innovation economy

    by Michael Tomberlin

    Access the article here.

    Video here.

  • 10 Feb 2022 12:17 PM | Anonymous member

    HudsonAlpha Expands Executive Leadership Amid Rapid Growth

    Dr. Neil Lamb to serve as President, Dr. Rick Myers to serve as Chief Scientific Officer

    HUNTSVILLE, Ala — As HudsonAlpha Institute for Biotechnology continues its rapid economic growth and advancements in genomics and life science research, the HudsonAlpha board of directors announced today the expansion of its executive leadership team. Richard Myers, PhD, current President and Science Director, will serve as HudsonAlpha’s new Chief Scientific Officer and President Emeritus. Neil Lamb, PhD, current Vice President for Educational Outreach, will serve as the new President of the Institute, effective July 1, 2022. 


    Momentum from growth and campus expansions have driven the need for an expanded executive team to intelligently manage the workload, maintain the vision, and prime the organization for continued success in the future. The Institute is a global leader in using advanced genomic technologies to solve challenges related to human health and modern agriculture, while simultaneously engaging and preparing tomorrow’s bioscience workforce. According to a recent study, HudsonAlpha has generated $3.2 billion economic impact for the state of Alabama between 2006 and 2020, with an increase of $750 million during 2019-2020. The campus is home to more than 1,100 employees and 48 associate life science companies.

     

    “Rick Myers and Neil Lamb have been critical to the success, innovation, and growth we’ve seen since Lonnie McMillian and I first launched HudsonAlpha,” said Jim Hudson, HudsonAlpha co-founder and chairman of the board. “With Neil’s vision and work ethic leading the organization along with the innovative research led by Rick, we are truly poised to amplify our work as HudsonAlpha’s reach and impact continue to grow.”


    Dr. Rick Myers has been with HudsonAlpha since its doors opened in 2008, serving as President and Science Director, and as the M. A. Loya Chair in Genomics since 2020. Dr. Myers came to HudsonAlpha from Stanford’s Human Genome Center, where he led a team that was a major contributor to the Human Genome Project—the international research effort that sequenced the entire human genome. Today at HudsonAlpha, researchers under Dr. Myers’ leadership apply genomic technology to uncover the causes of human diseases and accelerate discoveries in plants and agriculture. As Chief Scientific Officer, Dr. Myers will devote his focus to scientific discovery, achievement, and momentum while providing strategic support and guidance to Dr. Lamb.


    “At HudsonAlpha, our team is creating improvements for humankind everyday through research-based discoveries,” said Dr. Myers. “As we take our organization to the next level, it’s critical that we have the tools, resources, and team to continue advancing our research and applying our discoveries in the real world. It is this growth that drives my passion, gives me daily purpose, and excites me for our future. I truly believe the best is yet to come for HudsonAlpha.”


    Dr. Neil Lamb came to HudsonAlpha in 2006 with a calling to share his passion for human genetics and biotechnology with others through education. He has led HudsonAlpha’s educational outreach team from conception, creating innovative teacher training and toolkits, student experiences, public enrichment, and digital resources that have reshaped how science education is now delivered. Throughout his tenure as Vice President for Educational Outreach, Dr. Lamb has been a public ambassador for HudsonAlpha and a strategic internal advisor helping guide the Institute’s growth. As President, he will now drive the strategic vision and lead day-to-day operations for the entire organization.


    "Rick Myers is not only a close friend and mentor, but the person who introduced me to Jim Hudson and co-founder Lonnie McMillian in the early days of HudsonAlpha," said Dr. Lamb. “I would not be here if it weren't for Rick. He has positioned HudsonAlpha for continued growth and success, and I share his vision and excitement for the possibilities of the future. This expansion of our executive team will allow us to focus more resources on our mission and expand our local, regional, and global impact for years to come.”


    HudsonAlpha and resident associate companies co-located on the biotech campus in Cummings Research Park (CRP) have continued to expand their footprint in multiple sectors across the biosciences including research, testing and medical labs, pharmaceuticals, agriculture feedstock and chemicals, technology development and medical devices and equipment. The HudsonAlpha campus continues to expand, with new construction underway on a 13,000 square foot agricultural space and a 96,000 square foot global headquarters for resident associate company Discovery Life Sciences.


    With this executive expansion, HudsonAlpha will be seeking a new Vice President for Educational Outreach. Find more information in the coming days at www.hudsonalpha.org


    ###

    About HudsonAlpha: HudsonAlpha Institute for Biotechnology is a nonprofit institute dedicated to developing and applying scientific advances to health, agriculture, learning, and commercialization. The HudsonAlpha biotechnology campus consists of 152 acres nestled within Cummings Research Park, the nation’s second largest research park. The state-of-the-art facilities co-locate nonprofit scientific researchers with entrepreneurs and educators. HudsonAlpha is a national and international leader in genetics and genomics research and biotech education and fosters more than 48 diverse biotech companies on campus. To learn more about HudsonAlpha, visit hudsonalpha.org.


  • 26 Jan 2022 9:07 AM | Anonymous member

    BIO Alabama's CEO, Rachel Lane, PhD was appointed to the University of Alabama's Center for Convergent Bioscience and Medicine (CCBM) Scientific Advisory Board

    CCBM is dedicated to the convergence of bioscience and medicine with chemical, biological, physical, mathematical, and engineering disciplines. This collaborative approach will overcome obstacles in drug development to bridge the preclinical and clinical divide. 

    "I am honored to be a member of this advisory board and to serve with such distinguished scientists who represent various disciplines but one goal: a collaborative approach to improving the human condition through science," said Lane. "Alabama in general, and the University of Alabama specifically, are fortunate to have the vision and energy of Ravi Kumar, PhD leading this charge in our state."


  • 26 Jan 2022 5:25 AM | Anonymous member


    Jason Rupp joins the Acclinate team

    Jason brings 20 years of experience to lead Acclinate’s business development

    .

    Acclinate hires Jason Rupp as Head of Business Development effective January 20, 2022. Rupp brings nearly 20 years of business development experience to the company. 

    Before joining Acclinate, Rupp was President of Southeast Life Sciences (SLS), a trade association dedicated to supporting the life science community in the southeast. Among his many accomplishments at SLS, Rupp led the launch of SE Color, a division of SLS dedicated to advancing the issue of lack of diversity in clinical trials. Prior to his tenure as SLS, Rupp led business development for the Biotechnology Innovation Organization (BIO)and AdvaMed in Washington, DC. 

    Acclinate is committed to health equity through inclusive research. The addition of Rupp will ensure fairness in clinical trials that leads to better science and creates the potential to reduce health disparities. “Since launching the Diversity& Inclusion initiatives at SLS, I’ve learned the critical need to diversify our clinical trials,” Rupp said, “The opportunity to help address this need at Acclinate is truly an honor.” 

    “Jason’s business development experience, industry connections, and demonstrated focus on clinical trial diversity make him an ideal addition to our growing team,” said Del Smith, Acclinate’s CEO and co-founder.

    Mr. Rupp has a master’s in business administration from the University of Maryland and a bachelor’s degree in political science from Brigham Young University.

    ###

    About Acclinate™

    Acclinate™ is a Birmingham-based, digital health company helping pharmaceutical companies and healthcare organizations access and engage communities of color, so research is more inclusive.


    CONTACT

    Tiffany Whitlow

    256-435-2800 

    tiffany@acclinate.com                                                                          


  • 6 Dec 2021 7:29 AM | Anonymous member

    CERFLUX Receives $100,000 BCRFA Innovation Award

    Contact: Kathleen A. Lovelady | kal@CerFlux.com | https://CerFlux.com

    (Photographer Dustin Massey – Dustin Massey Studios)
    L-R: Dr. Lizhong Wang; Dr. Selvarangan Ponnazhagan; Dr. Rajeev Samant; Dr. Ahmed Elkhanany; Dr. Barry Sleckman; Ms. Beth Bradner Davis; Dr. Jamil Saad; Ms. Laura Hinton; Dr. Karim Budhwani; Dr. Laura Rogers; Dr. Lalita Shevde-Samant; Dr. Xu Feng

    The Breast Cancer Research Foundation of Alabama (BCRFA) has awarded CerFlux $100,000 Innovation award to fast-track research and development of the CerFlux Personalized Oncology Efficacy Test (POET)

    BIRMINGHAM, Ala., (December 6, 2021) – CerFlux, Inc., creators of advanced personalized medicine technology for identifying the most efficient and effective treatments for each cancer patient on an individualized basis, announced the receipt of a $100,000 grant from the BCRFA. Funding from this grant will help bolster research, development, and lab-to-life translation of its low-cost, rapid Personalized Oncology Efficacy Test (POET).

    More than 3.8 million women in the US have a history of breast cancer. This year an estimated 281,550 new cases of breast cancer will be diagnosed in the US. The Breast Cancer Research Foundation of Alabama supports innovative research that will help improve outcomes of patients with breast cancer. Since 1996, they have contributed almost $12 million dollars to breast cancer research. Despite the impact of COVID-19, BCRFA donated their largest amount to date. CerFlux is honored to have their support in their mission to #CrushCancer.

    What makes BCRFA support for CerFlux particularly noteworthy is the focus on lab-to-life translation of technological breakthroughs like POET in transforming cancer treatment around the world. Today, less than 3% of funded research makes such a lab-to-life leap. Further, while extensive biopharma research makes new treatment options available, the lack of tools to quickly select the right treatment for each patient on a personalized basis creates a frustrating dilemma in clinical decision-making. This is because every tumor is unique in its makeup and its response to treatment.

    Without personalized predictive tools like POET, treatment is based on generalized parameters such as age, disease stage, etc. often leading to a mismatch between treatments and tumors. Consequently, about 75% of patients – nearly 3 out of 4 – must endure first line chemotherapy which turns out to be ineffective because the treatment regimen does not match the patient’s tumor. This results in lost time and a substantial physical, emotional, and financial burden.

    CerFlux POET addresses this critical, urgent, and unmet need for accessible and affordable predictive technologies that identify optimal therapy regimens and strategically eliminate ineffective options. With BCRFA support, CerFlux is developing bioreactor technology to identify the most promising treatment strategies on a personalized basis using biopsy tissue from the patient’s own tumor. CerFlux already holds five patents on this technology with another five patents pending.

    “Accounts of cancer date back some 5,000 years and yet, “slash, poison, and burn” continue to remain predominant approaches to treatment. Knives, salts, pastes, and heavy metals of the past have evolved into surgery, chemotherapy, radiation, and combinations of the three. Despite recent advances in the field, socioeconomic impact of cancer continues to spiral out of control with 42% of patients depleting their entire life savings in just 2 years from diagnosis. Developing better tools for cancer treatment is not merely an intellectual exercise or business driver, but a mandate for us. We have designed our patented technology so that it can be applied across the cancer care continuum: POET to better match treatments to tumors and PEER (Preclinical Estimate Efficacy Report) to predict clinical success of new therapies still under development at pharmaceutical companies. Our goal is to transform both discovery and delivery of cancer treatment,” explains CerFlux CEO Dr. Karim Budhwani.

    "The BCRFA is pleased to again support the promising research being conducted by the CerFlux team," said Beth Bradner Davis, Executive Director of the Breast Cancer Research Foundation of Alabama. "Our organization's core mission is to find and fund projects that have a deep impact on breast cancer patients in Alabama and around the globe. CerFlux Personalized Oncology Efficacy Test (POET) is making great advances in treatment for cancer patients. We are proud to continue our partnership."

    Predictive technologies like POET – that match each patient with the right treatment regimen BEFORE treatment is administered – will transform cancer treatment in the near-term and make a difference in the lives of patients and their families, as well as providers around the world.

    About CerFlux, Inc.

    CerFlux, Inc., a Birmingham, Alabama, based biotech company, is creating advanced, personalized medicine solutions to rapidly identify the most effective cancer treatments for each patient on an individualized basis. While breakthroughs in biopharma discovery are helping to produce a library of treatment options, many new therapeutics are becoming more specialized and therefore effective for smaller populations. This underscores an even greater need for matching treatments to tumors on an individualized basis; ironically, cancer is a ubiquitous rare disease. Our goal is to build solutions that quickly and clearly separate optimal from ineffective options, so clinical teams can successfully treat the disease, thereby improving treatment outcomes and quality of life for cancer patients.

    Additional Information

    To request collateral materials for publication or to schedule interviews with principals from CerFlux, Inc., please contact Ms. Kathleen A. Lovelady at kal@CerFlux.com for availability.

  • 27 Oct 2021 10:25 AM | Anonymous member

    UAB Biotech Startup, Reliant Glycosciences, Enables Treatment for IgA Nephropathy

    Birmingham, AL / October 2021– Reliant Glycosciences, LLC (Reliant) is pleased to report its successful completion of a $200,000 Phase I SBIR Grant from the NIH. This grant has enabled Reliant to initiate the process of translating their proprietary biomarker tests for a kidney disease, IgA nephropathy (IgAN), to the clinical setting. Biomarkers are biological molecules in blood or tissues that can indicate normal or abnormal processes or a specific disease. Since its spin-off from UAB at the recommendation of Dr. Selwyn Vickers, Dean of the UAB Heersink School of Medicine, Reliant’s initial focus has been to provide measurements of potential disease-specific biomarkers for ongoing IgAN clinical trials.

    The Reliant team

    Reliant was formed in 2016 with the mission of enabling development of transformative and targeted treatments for IgAN by providing a means to characterize disease-specific biomarkers. The biotechnology company, located in Birmingham, AL, focuses on developing diagnostic and prognostic tools for patients with IgAN. IgAN, one of the most common forms of glomerulonephritis in the world, affects more than 150,000 Americans and is even more prevalent in other countries. Glomerulonephritides are diseases that injure glomeruli, the part of the kidney that filters waste products from the blood. Several of the Reliant founders helped define IgAN as an autoimmune disease wherein kidneys are injured as innocent bystanders.

    The company was founded by Drs. Bruce Julian, Jan Novak, Matt Renfrow, Will Placzek, and Dana Risk as a spinout company from UAB. The founders serve on the advisory board for the company. The company has taken advantage of the Discovery BioMed incubator headed by Dr. Erik Schwiebert, an established biotech entrepreneur in the Birmingham area. The company now has one full-time scientist and one full-time administrative employee. Janusz Tucholski, Ph.D. is the Lead Scientist at Reliant and served as the PI on the Phase I SBIR grant. He received his Ph.D. in 1996 from the University of Gdańsk, Gdańsk, Poland in Biochemistry. Dr. Tucholski guides and leads IgAN biomarker assays for Reliant. Tatum Street, MBA is the Communications Manager at Reliant. She received her MBA from the University of Alabama at Birmingham and is the team’s most recent hire, focusing on the internal and external communications of the company.

    As stated by one of the founders, Matt Renfrow, “Reliant Glycosciences started with the goal of getting the IgA nephropathy biomarker assays developed in Dr. Novak’s laboratory out to the market for wider use. The UAB Harbert Institute for Innovation and Entrepreneurship helped us make that happen through the licensing agreement and by becoming partners with us in the endeavor. We have a working team of experts, advisors, and scientists in the company that have successfully made these assays available for use by biopharmaceutical companies. The ultimate goal is to get these assays into nephrologists’ hands so they can monitor and better treat patients with IgA nephropathy.”

    To learn more about Reliant Glycosciences, see their website at

    https://www.reliantglycosciences.com/

    Written by: Tatum Street

    Updated 11/17/21

  • 2 Sep 2021 3:19 PM | Anonymous member

    BIO Alabama submitted the following letter to Governor Ivey, highlighting the tremendous work of our members in COVID-19 relief efforts.


    Dear Governor Ivey,

    As concern grows over the advances of the Delta variant COVID strain, we wanted to share the tremendous contributions Alabamians in our bioscience industry have made in this urgent fight. We live in a state that literally took man to the moon, and innovation is in our core, dating back to the agricultural technologies Dr. George Washington Carver developed at Tuskegee University. Now, our state’s bioscience community is assisting our neighbors, the US, and the rest of the world to curb this powerful pandemic’s destructive path by studying the virus, developing vaccines, and discovering new tools and treatments.

    • Avanti Polar Lipids (part of Croda International plc) utilized its Lipid Nanoparticle technology to enable the rapid clinical development of the Pfizer-BioNTech COVID-19 vaccine. Avanti was the first company to supply clinical and commercial quantities of this critical lipid technology that enables the targeted release of the mRNA vaccine to muscle tissue.
    • Moderna selected the vial produced by SiO2 Materials Science for its unique composition and manufacturing process. SiO2 increased vial production in 4 months to levels that would have taken 18-24 months for traditional vials. Without Avanti’s and SiO2’s technology and manufacturing capacity, many more lives may have been lost to the virus.
    • Data from a powerful artificial intelligence program developed at the Precision Medicine Institute of the University of Alabama at Birmingham resulted in the first dose-sparing cocktail of remdesivir, the only approved treatment for COVID.
    • At Auburn University, teams developed biosensors for rapid COVID-19 testing and reengineered standard CPAP machines into functional emergency ventilators.
    • The University of South Alabama collaborated with partners to repurpose their 3D printing capabilities to produce PPE for local healthcare workers.
    • The HudsonAlpha Institute for Biotechnology’s powerful sequencing technology tracked the shift in COVID variants, noting the predominance of the Delta variant by June 2021.
    • The University of Alabama spearheaded a vaccination equity campaign, focusing on the Black Belt, which currently leads the state in vaccination status.
    • The University of Alabama at Huntsville collaborated with partners, including Hewlett-Packard Enterprise, Alabama Supercomputer Center and Oak Ridge National Laboratory, to identify anti-COVID-19 chemicals and drug candidates.
    • CFD Research is developing a new class of COVID-19 drugs with the Defense Health Agency. 
    • Southern Research has conducted >$30 million of COVID-related research, using high-throughput screening to refine treatments, co-create vaccines, and develop assays for variant detection.

    As we continue to wage war against this unrelenting virus, we must celebrate the meaningful innovations Alabama is making so that we can emerge on the other side with confidence in each other and strength together. Governor Ivey, please share these major contributions with your staff and other elected officials so that we can appreciate the united contributions of our fellow Alabamians.

    Sincerely,

    Rachel Lane, PhD, RD

    Executive Director, BIO Alabama


  • 13 Aug 2021 10:04 AM | Anonymous member

    Dr. Lane penned a few thoughts on Alabama's bioscience industry and the role of BIO Alabama in growing it.

    https://www.thisisalabama.org/2021/08/10/how-bioscience-could-become-alabamas-next-big-industry/

  • 26 Jul 2021 10:01 AM | Anonymous member

    Sam Prickett chatted with BIO AL executive director Rachel Lane PhD, RD about BIO Alabama.

    https://www.thisisalabama.org/2021/07/26/new-trade-association-advances-alabamas-biotechnology-sector/

  • 15 Jul 2021 9:56 AM | Anonymous member

    BIO Alabama in Mobile

    July 12-13

    BIO Alabama executive director – Dr. Rachel Lane – wrapped up her listening campaign in mid-July with a visit to Mobile. The beauty and comradery of the city was evident, from the exquisitely landscaped campus of the University of South Alabama to the warm embraces shared by all members of the BIO AL roundtable.

    Left to right | Ashely Lindsey (BIO AL Mobile Ambassador), Michelle Parvinrouh (Executive Director of Innovation Portal), and Rachel Lane (Executive Director of BIO AL) at the Innovation Portal celebrate the Mobile spirit of making good things happen.

    Michael Berson of Adams and Reese LLP generously hosted Dr. Lane’s visit with key community leaders: Anitra Belle-Henderson (Executive Director of Communications and External Affairs at City of Mobile), Michael Chambers (Associate Vice President for Research at the University of South Alabama), Todd Greer (Vice President For Academic Affairs at the University of Mobile), Ashley Lindsey (Assistant Professor of Biology and the University of Mobile and BIO Alabama Ambassador), Michelle Parvinrouh (Executive Director at Innovation Portal), and Christina Stimpson (Director of Economic Development at Mobile Area Chamber of Commerce). Notably, this was the only meeting on Dr. Lane’s listening campaign to host a female majority. After the roundtable, Dr. Lane toured the incredible facilities at Innovation Portal. She was also excited to learn that both the University of South Alabama and the University of Mobile have implemented NSF I-Corps programs, a tremendous tool for exploring the commercial potential of scientific discoveries.

    According to 2018 workforce data published in the 2020 Bioscience Teconomy report, Mobile is a key player in Alabama’s life science workforce.  Alabama has a specialized workforce in Agricultural Feedstock and Industrial Biosciences, meaning that compared with the national average, the state has a significantly greater job concentration for this industry subsector. Mobile is the largest metropolitan statistical area (MSA) in AL to host a specialized workforce, and the only MSA in the state to land on a “top twenty” list, tailing Madison, WI for total number of employees in this industry subsector. Business Facilities – a key voice in the site selection marketplace – recently recognized Mobile as one of the top five best business environments (population <200,000) in the US, highlighting the distinct potential of this singular city to support bioscience growth. Mobile’s academic R&D capabilities, manufacturing specialty, innovation support, and favorable business environment create a unique microcosm with immense bioscience potential.

    The roundtable offered helpful insight into how these exceptional features of Mobile’s bioscience industry could fit into the state’s bioeconomy. Leaders expressed sincere interest in uniting Alabama’s bioscience presence and identifying a clear strategy for positioning the state for industry success.


Connecting the Bioscience Ecosystem in Alabama

BIO Alabama
P.O. Box 583
Arab, AL 35016


administrator@bioalabama.com

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